Yes! The Women’s Health Initiative Trial proved to us that synthetic hormones, such as premarin (horse estrogen) and progestin (synthetic progesterone) are unsafe. These are the chemical components that make up birth control pills and Prempro. When the trial was published the medical community was advised to take all post-menopausal women off of hormone replacement because of the side effects and bad outcomes observed in the trial. However, there have been many follow up studies to the WHI trial that have used bioidentical hormones and none of them have shown any such side effects. In fact, these studies have shown that bioidentical hormones, in doses physiologically produced by the human body, can restore health and balance without any long term side effects. In addition, it’s interesting to note that the same recommendations for taking post-menopausal women off synthetic hormones has not carried over to birth control pills, implants, or IUD’s, all of which have been shown to increase risk of blood clots and cause many other similar side effects. In fact, it is well known that birth control, or any type of hormone use, is associated with B vitamin depletion, which can create many other health problems such as unexplained skin rashes, anxiety/depression, memory loss, heart and neurological disorders. If you are currently taking any type of hormones, whether natural or synthetic, you should also be taking a vitamin B complex on a daily basis.